Odam SG*, Shippman J
Cell therapy has emerged as a ground-breaking approach in the field of immunology, presenting new opportunities for the treatment of various immunological conditions. This innovative therapeutic strategy involves utilizing living cells to enhance or suppress the immune response, depending on the specific disease being targeted. In this abstract, we explore the applications of cell therapy in immunological disorders, including autoimmune diseases, cancer immunotherapy, immunodeficiencies, allergic disorders, and transplantation. Specifically, we discuss the use of regulatory T-cells (Tregs) to suppress autoimmunity, chimeric antigen receptor T-cell (CAR-T) therapy for cancer treatment, and hematopoietic stem cell transplantation (HSCT) for immunodeficiencies. Furthermore, we highlight the challenges associated with cell therapy, including safety concerns, personalized approaches, cost, and long-term efficacy. Despite these challenges, cell therapy holds great promise, paving the way for transformative advancements in immunology and offering hope for improved treatment outcomes and potential cures for patients with immunological conditions. Continued research and development in this area will undoubtedly shape the future of immunology and pave the way for personalized, effective, and accessible cell-based treatments.
KeywordsCell therapy; Immunology; Autoimmune disorders; Cancer immunotherapy; Regulatory T-Cells; Chimeric antigen receptor T-Cells (CAR-T); Hematopoietic stem cell transplantation (HSCT); Immunodeficiency