Andrzej Rykowski
The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phosphorylase with Ki values in the 10-3 –10-5 M range.
KeywordsThiazine; Purine analogues; Enzyme inhibitors; Spectroscopic probes.